Current Studies

We are currently supporting the following studies which are recruiting general practices now. To find out more, simply call us on 01223 967855 or follow the joining information provided for your study of interest.

Study Description Recruitment Period Joining Information
MAGNIFY Primary care cluster randomised trial in COPD involving patient adherence support.
Disease area: COPD
Sponsor: OPRI
Approvals: REC ref 19/EM/0238
NIHR CRN portfolio: CPMS 42625
Now to June 2020 E:
T: 01223 967855
IMP2ART Primary care cluster randomised trial in asthma involving patient asthma action plans.
Disease area: Asthma
Sponsor: University of Edinburgh
Now to December 2020 E:
ADxDA Qualitative study to develop a clinical decision support system to improve asthma diagnosis in primary care.
Disease area: Asthma
Sponsor: University of Edinburgh
Now to June 2020

What is the study?

A pragmatic, cluster randomised, multicentre implementation study over one year. Participating practices will be randomised to either of two arms:
● Adherence support arm – provision of adherence technology support devices
● Standard of care arm – continue usual routine clinical care
There are no study visits. Provision of adherence technology support devices will take place at routine COPD reviews. De-identified Electronic Medical Record (EMR) data collected from all participating practices by Optimum Patient Care (OPC) will be used to assess clinical outcomes.

The competitive recruitment process is now open on a first come – first served basis, with a rolling start for study implementation in the practices. Expressions of interest can be made to or 01223 967855.

The IMP2ART study aims to facilitate the provision of supported self-management in routine primary  care practice.

To do this, we need to develop practical strategies to enable practices to prioritise  supported self-management for people with asthma, motivate and skill healthcare professionals, and  provide access to resources for patients.

What IMP2ART will do:

  1.  Identify effective resources to support patients
  2. Provide training for professionals
  3. Help practices to fit supported self-management within their organisational routines  We will pilot the approach in a small number of UK general practices and then evaluate the strategy  in a UK-wide RCT.

If successful, our implementation strategy will be immediately ready for roll-out to  benefit people with asthma and the NHS.

How Can You Help?

We need:

  • People who work in primary care (nurses, doctors, admin staff etc.) to contribute to an  advisory board
  • Practices to help with developing and piloting components of the implementation strategy
  • 144 practices to participate in the trial

IMP2ART is led by two GPs: Professor Hilary Pinnock and Professor Steph Taylor.  Dr Victoria Hammersley is the Programme Manager.

For more information please read the IMP2ART information sheet.

To find out more please email: and help make IMP2ART a success!

IMPlementing IMProved Asthma self-management as RouTine  (IMP2ART)

Substantial over- and under-diagnosis of asthma is occurring in routine clinical practice in both, children and adults. This study aims to develop and test an Asthma Diagnosis clinical decision support system for primary care. It will be designed to aid health professionals to consider the likelihood of asthma and recommend the most valuable next steps to enable an accurate and timely diagnosis. Also, the system will be tailored to meet the needs of primary care staff and fit within the routines of individual practices.

Decision support systems only work if they are used. Therefore, the focus of ADxDA is understanding more about how asthma is currently diagnosed; what would be most valuable to staff and patients; and how to integrate the digital decision support system so it operates seamlessly alongside existing practice software.

As a part of the investigation, the study team at the University of Edinburgh will be conducting short interviews with participating GPs and nurses who are involved in diagnosing asthma. Practices would also be asked to send out invitation letters to a random sample of patients with ‘active’ asthma to invite them to join small group-based discussions or an individual interview.

Practice payments for participation will be in line with Clinical Research Network rates of £80 / hour for GPs and £30 / hour for nurses.

OPC are currently recruiting practices in Leeds, Birmingham and Solihull, Norwich, Greater Yarmouth and Waveney and Norfolk CCGs to participate in ADxDA. To find out more about the study please see the practice information leaflet or visit the ADxDA website here.

If you are interested in taking part, or have any further questions, please contact Victoria Murray at or the OPC team at

What is the study?

A randomised controlled trial of GP practice staff training and high risk patient identification and flagging to reduce the occurrence of severe asthma related events. You can find the  full study summary here.

It is funded by the NHS’ National Institute for Health Research’s Health Technology Assessment Programme.


The ASSIST Study, a collaboration among REACH, ASU Educational Outreach & Student Services, and the Department of Psychology, seeks to better understand the challenges students face as they move from high school into the college environment. The primary goal of ASSIST is to learn from ASU incoming students in order to develop a web-based prevention program that promotes strategies and tools for a successful college transition. ASSIST uses a multi-method approach, including twice-weekly diaries, questionnaires, focus groups, and academic records, to assess students and parents before, during, and after the transition to college to better understand the experiences and coping strategies that predict success and well-being. These data will directly inform the design of support services for parents and students in an effort to increase the likelihood of positive adjustment and decrease problematic behavior and drop out.


What is the study?

A cross-sectional, electronic survey to validate a new methotrexate treatment adherence tool in rheumatoid arthritis (RA) – METNA RA study. This is a multicentre, electronic questionnaire study using data from the Optimum Patient Care Research Database (OPCRD) collected from participating general practices. The study is aimed at patients taking oral methotrexate as treatment for rheumatoid arthritis for at the last 12 months or longer.

Study Conduct & Work Involved

The study involves minimal work from a practice, as we appreciate the staff and time limitations for practices. We will provide the practice with dedicated research coordinator(s) to be part of the practice research team to support with work required for the study.

The study is conducted online via the secure study portal – Clinpal, to make participation easy for both your practice and patients. Clinpal will support all essential steps from patient invitation, consenting and questionnaire completion, through to closure, and will help you track your patients’ progress through the study.

Study Payment

The practice will receive compensation of £340 for site set-up, maintenance and close out; and £55 per completed patient. Invoice for payment can be raised as soon as recruitment has been maximised for your practice and all the GP questionnaires are completed.


We have finished recruiting for practices to take part in this ethically approved clinical trial.